Nimesulide gel (leaflet) what it is for, how to apply, contraindications and side effects

The information presented here are based on the original package insert of the medicine, We also consult professionals in the field, ensuring the accuracy and reliability of the data.

Understanding a leaflet can be complicated, but at Tenho Saúde we simplify the information so that you can easily understand every detail. Therefore, always consult first Tenhosaude.com for information about medications.

At the end of this article, you can download the complete and original package insert.

We recommend that you read it carefully. If you have any questions, consult your doctor or pharmacist for personalized guidance.

What is Nimesulide gel for?

THE nimesulide gel It is an anti-inflammatory and analgesic that we use to locally treat inflammation and pain in general. It is especially indicated to relieve the following painful and inflammatory conditions:

• Sprains and strains: Injuries that affect our muscles, ligaments and tendons.
• Muscle pain: Which arise after physical exertion or due to injuries.
• Arthritis and bursitis: Inflammatory conditions of our joints and bursae (pouches of fluid that reduce friction in the joints).
• Tendinitis: Inflammation of our tendons.
• Traumatic pains: Resulting from bruises, knocks, or other injuries.

We apply the gel directly to the painful area, to relieve and reduce inflammation topically and locally.

How does Nimesulide gel work?

THE nimesulide gel It acts as an anti-inflammatory and analgesic. When we apply the gel to the skin, it inhibits the action of substances that cause inflammation and pain in our body.

In this way, the medicine relieves pain and helps reduce edema (swelling) in the inflamed area, providing localized relief.

What should I know before using Nimesulide gel?

Allergic reactions and sensitivity

We should notify our doctor if any reactions occur. Some more sensitive patients may experience allergic reactions at the injection site, such as swelling, irritation and peeling of the skin. In rare cases, asthma may occur as an allergic reaction.

Application in healthy location

Nimesulide gel should only be applied to healthy areas of the body. Do not use the product on wounds, burns, open lesions, infections or other similar conditions. Avoid contact with the eyes and mucous membranes. If accidental contact with the eyes occurs, rinse immediately with water. Remember that nimesulide is for topical use (on the skin) and should not be ingested.

Stains on clothes

Nimesulide gel may stain clothing. If this occurs, it is recommended that the clothing be washed with hot water and mild soap.

Use with other anti-inflammatories

Avoid using together with oral (non-steroidal) anti-inflammatory drugs. The use of other topical anti-inflammatory drugs together with nimesulide gel may cause a burning sensation and, in rare cases, skin reactions due to sun exposure.

Special care if you have these symptoms:

Patients with gastrointestinal bleeding, active or suspected peptic ulcer disease, severe liver or kidney dysfunction, severe clotting problems, or severe uncontrolled heart failure should be careful when using this medication as it may aggravate these health problems.

Where and how should I store it?

Storage:
Store at room temperature, between 15 and 30ºC, protect from light and humidity, store in its original packaging and keep out of the reach of children.

Information on the packaging:

• Check the batch number and manufacturing and expiration dates on the packaging.
• Do not use the medicine after the expiration date.

Aspect:
Observe the appearance of the gel; it should be opaque, homogeneous, slightly yellowish, and free of granules and impurities. Before using, evaluate the appearance. If there is any change, even within the expiration date, consult a pharmacist to confirm the safety of use.

Ingredients, nutritional table and composition

*carbomer 934, methylparaben, propylparaben, trolamine, propylene glycol, ethoxylated hydrogenated castor oil, isopropyl alcohol, purified water.

When should I not use Nimesulide gel?

• We should not apply the gel to cracked, open skin, skin with local infection, wounds or burns. 
• It should not be used together with other topical creams. 
• It is not recommended for pregnant or breastfeeding women, unless authorized by your doctor.
• Allergy to any ingredient in the formula, to acetylsalicylic acid or to other anti-inflammatories
• It is contraindicated for children under 12 years of age.

How to use Nimesulide gel?

1. Evaluate the application site: It is not recommended to apply the gel to cracked, open skin, skin with local infection, wounds or burns. If the area does not present these conditions, proceed with the application.
2. Application: Apply nimesulide gel to the affected area twice a day.
3. Massage: Lightly massage the gel until the color disappears and the gel is completely absorbed.
4. Care after application: Avoid washing the application site in the first few hours after application. Only wash your hands immediately after applying the gel to avoid contamination with medication residue, which may come into contact with food, nose, mouth, eyes and other areas.

Duration of treatment: Use the medicine for a period of 7 to 15 days.
Discontinuation of use: If irritation occurs at the application site, discontinue treatment.

If symptoms persist or do not improve, consult a pharmacist, doctor or dentist.

What should I do if I forget to use it?

If you forget to use your medication, apply it as soon as you remember.

If it is close to the time of your next dose, skip the missed dose and continue with your regular dosing schedule.

Side effects and adverse reactions

Topical use of nimesulide gel generally has a low chance of causing side effects. However, the following may occur:

• Common reactions (1% to 10% of patients): itching and redness at the application site.
• Very rare reactions (less than 0.01% of patients): allergic reactions such as asthma, swelling of the face due to allergies, and redness all over the body.
• Reactions that are not accurate: swelling, small blisters and peeling skin.

What to do if you use more than the recommended amount?

There are no known symptoms of overuse of nimesulide gel, as topical application does not cause high concentrations in the blood. However, if you use too much gel and experience adverse effects or accidentally ingest it, follow these steps:

1. In case of accidental ingestion: Contact a doctor or go to an emergency room immediately. Report the amount ingested, the time of ingestion, and any symptoms observed. Also take the packaging and the medicine with you.
2. If a large amount of the medicine is used: Seek medical help immediately. If possible, bring the medicine packaging or leaflet with you to provide detailed information.

For further guidance: Call 0800 722 6001.

Download the original manufacturer's leaflet:

Click the button below and download the Manufacturer's complete leaflet:

Sources and bibliography:

This article was extracted from the original package insert. Nimesulide Gel 20 mg/g [Package insert], Laboratory: EMS Inc. located in Journalist Rod. Francisco Aguirre Proença, in August 30, 2024, under technical supervision of the responsible pharmacist.

To check the leaflet of other brands, you can visit ANVISA electronic bulletin board and search for the manufacturer of your choice.