{"id":4086,"date":"2023-06-03T22:35:08","date_gmt":"2023-06-04T01:35:08","guid":{"rendered":"https:\/\/tenhosaude.com\/?p=4086"},"modified":"2024-08-20T22:59:43","modified_gmt":"2024-08-21T01:59:43","slug":"neosoro-nafazolina-bula-como-tomar-contraindicacoes-efeitos-colaterais","status":"publish","type":"post","link":"https:\/\/tenhosaude.com\/en_au\/neosoro-nafazoline-leaflet-how-to-take-contraindications-side-effects\/","title":{"rendered":"Neosoro\u00ae (naphazoline): leaflet, how to take, contraindications and side effects."},"content":{"rendered":"<h2 id=\"o-que-e\" class=\"wp-block-heading\">What is it?<\/h2>\n\n\n\n<p><strong>Neosoro\u00ae<\/strong> \u00e9 uma marca registrada de um medicamento nasal\u00a0a base de\u00a0<strong>naphazoline hydrochloride<\/strong>, being an antiseptic and nasal fluidifier, widely used to relieve symptoms of nasal congestion.<\/p>\n\n\n\n<p>It is known for its effectiveness in providing quick and lasting relief, facilitating breathing and promoting a feeling of well-being, making it a reliable product for treating nasal discomfort.<\/p>\n\n\n\n<h2 id=\"para-que-serve\" class=\"wp-block-heading\">What is it for?<\/h2>\n\n\n\n<p>Neosoro\u00ae is indicated for the relief of nasal congestion, which can be caused by different conditions, including colds, flu, rhinitis, sinusitis and allergies.\u00a0<\/p>\n\n\n\n<p>Nasal congestion is characterized by the narrowing of blood vessels in the upper airways, caused by the mucous membrane, resulting in difficulty breathing, a feeling of heaviness in the nose and general discomfort.\u00a0<\/p>\n\n\n\n<p>Neosoro\u00ae acts directly on these symptoms, providing effective and immediate relief.<\/p>\n\n\n\n<h2 id=\"como-funciona-farmacodinamica-e-farmacocinetica\" class=\"wp-block-heading\">How does it work? Pharmacodynamics and Pharmacokinetics<\/h2>\n\n\n\n<p>The active ingredient in Neosoro\u00ae is naphazoline, a substance that is a vasoconstrictor. Naphazoline acts by stimulating the alpha-adrenergic receptors present in the blood vessels of the nose.\u00a0<\/p>\n\n\n\n<p>This action promotes the constriction of blood vessels, resulting in a reduction in swelling and nasal congestion. In this way, Neosoro\u00ae unblocks the airways, allowing for freer and more comfortable breathing.<\/p>\n\n\n\n<p>After nasal application of Neosoro\u00ae, naphazoline is rapidly absorbed by the nasal mucosa. It usually begins to take effect about 10 minutes after application, and its effect lasts between 2 and 6 hours. The substance is metabolized mainly in the liver and excreted mainly by the kidneys.<\/p>\n\n\n\n<h2 id=\"como-devo-usar\" class=\"wp-block-heading\">How should I use it?<\/h2>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Before using, make sure it is not expired.<\/li>\n\n\n\n<li>Drop 1 to 2 drops into each nostril (nose), 4 to 6 times a day.<\/li>\n\n\n\n<li>Do not exceed the maximum daily dose of 24 drops.<\/li>\n\n\n\n<li>After use, wipe the applicator with a dry tissue and replace the protective cap.<\/li>\n\n\n\n<li>Respect a minimum interval of 3 hours between applications.<\/li>\n\n\n\n<li>Avoid using the product for more than 3 to 5 consecutive days and do not exceed the recommended dose.<\/li>\n<\/ol>\n\n\n\n<p>Remember that Neosoro\u00ae is intended for nasal use only and should not be swallowed. To reduce the risk of contamination and transmission of infections, avoid sharing the bottle with others.<\/p>\n\n\n\n<h2 id=\"contraindicacoes-e-advertencias\" class=\"wp-block-heading\">Contraindications and warnings<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Neosoro\u00ae Adult should not be used by children under 12 years of age. For children over 2 years of age, purchase Neosoro\u00ae Children.<\/li>\n\n\n\n<li>Pregnant women: use without medical supervision is not recommended.<\/li>\n\n\n\n<li>Do not use if you are allergic to any component of the formula.<\/li>\n\n\n\n<li>It should not be used in people with narrow-angle glaucoma.<\/li>\n\n\n\n<li>During use, it is recommended not to drive vehicles or operate machinery, as the medication may affect ability and attention, causing drowsiness or other effects that may compromise safety in these activities.<\/li>\n\n\n\n<li>People who have the following conditions should inform their doctor before starting and be more careful when using it:\n<ul class=\"wp-block-list\">\n<li>Bronchial asthma,\u00a0<\/li>\n\n\n\n<li>Cardiovascular problems (heart and blood vessels),<\/li>\n\n\n\n<li>High blood pressure (hypertension),\u00a0<\/li>\n\n\n\n<li>Hyperthyroidism (overactive thyroid);<\/li>\n\n\n\n<li>Diabetes mellitus (high glucose levels);<\/li>\n\n\n\n<li>Prostatic hypertrophy (enlarged prostate).\u00a0<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n\n\n\n<h2 id=\"efeitos-colaterais\" class=\"wp-block-heading\">Side effects<\/h2>\n\n\n\n<p>Neosoro\u00ae may cause some adverse reactions. Here we list the main ones:<\/p>\n\n\n\n<p><strong>Transient local irritation:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Burning<\/li>\n\n\n\n<li>Burning\u00a0<\/li>\n\n\n\n<li>Sneezing<\/li>\n<\/ul>\n\n\n\n<p><strong>General side effects:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Nausea (feeling sick)<\/li>\n\n\n\n<li>Headache<\/li>\n\n\n\n<li>Increased blood glucose levels in diabetic patients who use the drug chronically<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Rebound nasal congestion (a condition in which sudden cessation of treatment leads to a return of symptoms)<\/li>\n\n\n\n<li>Drug-induced rhinitis caused by prolonged use of the drug<\/li>\n<\/ul>\n\n\n\n<p><strong>Cardiovascular reactions:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>High blood pressure (hypertension)<\/li>\n\n\n\n<li>Tachycardia (increased heart rate)<\/li>\n\n\n\n<li>Caution in elderly patients with severe heart disease and arrhythmias, as systemic absorption of naphazoline may aggravate these conditions.<\/li>\n<\/ul>\n\n\n\n<p><strong>Endocrine\/metabolic reactions:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Worsening of hyperglycemia (excess blood glucose) in patients with diabetes, especially those with diabetic ketoacidosis<\/li>\n<\/ul>\n\n\n\n<p><strong>Neurological reactions:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Drowsiness,\u00a0<\/li>\n\n\n\n<li>Piece of cake<\/li>\n\n\n\n<li>Decrease in body temperature<\/li>\n\n\n\n<li>Fatigue<\/li>\n\n\n\n<li>Tiredness<\/li>\n\n\n\n<li>Headache<\/li>\n\n\n\n<li>Eat<\/li>\n\n\n\n<li>Insomnia<\/li>\n<\/ul>\n\n\n\n<p><strong>Respiratory reactions:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Epistaxis (nosebleed)<\/li>\n\n\n\n<li>Burning and pain in the nose<\/li>\n\n\n\n<li>Sneezing<\/li>\n\n\n\n<li>Runny nose and discomfort<\/li>\n\n\n\n<li>Rhinitis<\/li>\n<\/ul>\n\n\n\n<p><strong>Ophthalmic reactions:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Conjunctivitis<\/li>\n\n\n\n<li>Eye irritation and pain<\/li>\n\n\n\n<li>Visual changes<\/li>\n\n\n\n<li>Eye redness and irritation<\/li>\n\n\n\n<li>Pupil dilation<\/li>\n\n\n\n<li>Increased intraocular pressure<\/li>\n<\/ul>\n\n\n\n<p><strong>Other adverse reactions described:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Benzalkonium chloride can cause rhinitis medicamentosa when used repeatedly. This manifests as inflammation, swelling, and nasal congestion.<\/li>\n\n\n\n<li>Do not ingest the medication, as it is intended for nasal use only. Ingestion may cause side effects such as nausea, vomiting, tachycardia, drowsiness, among others.<\/li>\n<\/ul>\n\n\n\n<p>In case of unusual side effects, it is important to notify the drug manufacturer and also register the incident in the Adverse Drug Event Reporting System \u2013 Vigimed. You can access it through the website:<a href=\"http:\/\/portal.anvisa.gov.br\/vigimed\" target=\"_blank\" rel=\"noopener\"> http:\/\/portal.anvisa.gov.br\/vigimed<\/a>.<\/p>\n\n\n\n<h2 id=\"composicao\" class=\"wp-block-heading\">Composition:\u00a0<\/h2>\n\n\n\n<p>Each mL of Neosoro\u00ae solution may contain:<\/p>\n\n\n\n<figure class=\"wp-block-table is-style-stripes\"><table class=\"has-gray-200-background-color has-background\"><thead><tr><th>Component<\/th><th>Amount<\/th><\/tr><\/thead><tbody><tr><td>Naphazoline hydrochloride<\/td><td>0.5 mg<\/td><\/tr><tr><td>Vehicle qsp (benzalkonium chloride, sodium chloride and water)<\/td><td>Sufficient quantity to reach 1mL<\/td><\/tr><\/tbody><\/table><figcaption class=\"wp-element-caption\">Composition table of Neosoro\u00ae (naphazoline hydrochloride)<\/figcaption><\/figure>\n\n\n\n<p>*Each mL corresponds to 30 drops.<\/p>\n\n\n\n<p>*Each drop of the solution contains 0.017 mg of naphazoline hydrochloride.\u00a0<\/p>\n\n\n\n<p>This information is important to ensure the correct dosage and administration of the medication. Consult the leaflet of the specific medication you are using to check the composition and excipients present. There may be variations between different brands\/products.<\/p>\n\n\n\n<h2 id=\"informacoes-tecnicas\" class=\"wp-block-heading\">Technical information:\u00a0<\/h2>\n\n\n\n<p>The information below refers to the active ingredient Nafazoline:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>F\u00f3rmula molecular:\u00a0C<sub>14<\/sub>H<sub>14<\/sub>N<sub>2<\/sub><\/li>\n\n\n\n<li>N\u00famero CAS:\u00a0835-31-4<\/li>\n\n\n\n<li>Massa molar:\u00a0210,274\u00a0g\/mol<\/li>\n\n\n\n<li>Nome IUPAC:\u00a02-(naphthalen-1-ylmethyl)-4,5-dihydro-1H-imidazole<\/li>\n<\/ul>\n\n\n\n<h2 id=\"nomes-comerciais-e-similares-do-neosoro\" class=\"wp-block-heading\">Trade names and similar names of Neosoro\u00ae<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Neosoro\u00ae H2: contains, in addition to naphazoline, benzalkonium chloride, a nasal antiseptic.<\/li>\n\n\n\n<li>Neosoro\u00ae Infantil: a lower concentration of naphazoline (0.25 mg\/mL) and is indicated for children over 2 years old.<\/li>\n\n\n\n<li>Rhino: contains only sodium chloride (physiological serum) and does not have a decongestant action, but rather a humidifying and fluidifying effect on nasal secretions.<\/li>\n<\/ul>\n\n\n\n<p>There are also other medicines that contain naphazoline in their composition, but with different commercial names, such as:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Nose.<\/li>\n\n\n\n<li>Multiserum.<\/li>\n\n\n\n<li>Naridrin.<\/li>\n\n\n\n<li>Nafazol.<\/li>\n\n\n\n<li>Nasolin.<\/li>\n\n\n\n<li>Nasal.<\/li>\n\n\n\n<li>Nasoflux.<\/li>\n\n\n\n<li>Nasomax.<\/li>\n\n\n\n<li>New serum.<\/li>\n\n\n\n<li>Rinofluimucil: which contains, in addition to naphazoline, acetylcysteine, a mucolytic that helps dissolve nasal mucus.<\/li>\n<\/ul>\n\n\n\n<h2 id=\"interacoes-com-outros-medicamentos\" class=\"wp-block-heading\">Interactions with other medicines<\/h2>\n\n\n\n<p>It is important to be careful when using Neosoro\u00ae if you are being treated with medicines known as monoamine oxidase inhibitors, such as phenelzine, tranylcypromine and moclobemide. These medicines can increase the blood pressure raising effects of naphazoline.<\/p>\n\n\n\n<p>Additionally, if you are taking tricyclic antidepressants such as amitriptyline, imipramine or clomipramine, it is recommended to exercise caution when using Neosoro\u00ae, as there may be an increase in blood pressure.<\/p>\n\n\n\n<p>\u00c9 importante lembrar que essas intera\u00e7\u00f5es medicamentosas n\u00e3o s\u00e3o exclusivas da nafazolina, mas \u00e9 essencial considerar essa possibilidade.\u00a0Informe sempre ao seu m\u00e9dico se estiver usando outros medicamentos.<\/p>\n\n\n\n<h2 id=\"superdose-o-que-acontece-se-tomar-acima-do-que-a-recomendada\" class=\"wp-block-heading\">Overdose: what happens if you take more than the recommended amount?<\/h2>\n\n\n\n<p>Excessive application of Neosoro\u00ae may cause adverse effects such as nasal redness, cardiac arrhythmias, decreased or increased heart rate, headache, nausea and vomiting, depression of the Central Nervous System, drop or increase in blood pressure.<\/p>\n\n\n\n<p>If you take too much medication, seek medical help quickly and take the medicine packaging or leaflet with you. For further guidance, you can also call 0800 722 6001.<\/p>\n\n\n\n<h2 id=\"download-da-bula-original\" class=\"wp-block-heading\">Download the original leaflet<\/h2>\n\n\n\n<p>Click on the button below and download the complete Neo Qu\u00edmica Manufacturer&#039;s leaflet.<\/p>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link has-green-background-color has-background wp-element-button\" href=\"https:\/\/tenhosaude.com\/wp-content\/uploads\/2024\/08\/Bula-do-paciente-NEOSORO-cloridrato-de-nafazolina-Neo-quimica-Brainfarma-Tenho-Saude.pdf\">Click here to download the leaflet<\/a><\/div>\n<\/div>\n\n\n\n<p>For more news, visit our website\u00a0<a href=\"https:\/\/tenhosaude.com\/en_au\/\">I am healthy<\/a>, follow on Instagram\u00a0<a href=\"https:\/\/www.instagram.com\/tenhosaude\/\" target=\"_blank\" rel=\"noreferrer noopener\">@tenhosaude<\/a>\u00a0and on TikTok\u00a0<a href=\"https:\/\/www.tiktok.com\/@tenhosaude.com\">@tenhosaude.com<\/a>.<\/p>\n\n\n\n<p class=\"has-gray-200-background-color has-background has-small-font-size\"><strong>Sources and bibliography:<\/strong><br><br>This article was manually extracted from the original package insert of the medicines produced by <a href=\"https:\/\/www.neoquimica.com.br\/nossas-marcas\/Neosoro\" target=\"_blank\" rel=\"noreferrer noopener\">Neo Qu\u00edmica\u00ae 30mL<\/a> in June 2022, under the technical supervision of the responsible pharmacist.<br><br>To access the Neosoro\u00ae or Nafazolina leaflet, you can visit\u00a0<a href=\"https:\/\/consultas.anvisa.gov.br\/#\/bulario\/\" target=\"_blank\" rel=\"noreferrer noopener\">ANVISA electronic bulletin board<\/a>\u00a0and search for the manufacturer of your choice.<\/p>","protected":false},"excerpt":{"rendered":"Learn the precise indications for Neosoro\u00ae and important information about its use, based on its official leaflet. We explain everything clearly and easily to understand, so that you have complete knowledge about this medicine.","protected":false},"author":1,"featured_media":4090,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[354],"tags":[260,255,257,182,252,254,253,235,258,259],"class_list":{"0":"post-4086","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-saude-mental","8":"tag-alergia","9":"tag-congestao-nasal","10":"tag-gripe","11":"tag-medicamentos","12":"tag-nafazolina","13":"tag-nariz-entupido","14":"tag-neosoro","15":"tag-remedio","16":"tag-resfriado","17":"tag-sinusite","18":"cs-entry","19":"cs-video-wrap"},"jetpack_featured_media_url":"https:\/\/tenhosaude.com\/wp-content\/uploads\/2023\/06\/Neosoro\u00ae-nafazolina-bula-como-tomar-contraindicacoes-e-efeitos-colaterais.-Tenho-Saude.jpg","jetpack_sharing_enabled":true,"jetpack_likes_enabled":false,"_links":{"self":[{"href":"https:\/\/tenhosaude.com\/en_au\/wp-json\/wp\/v2\/posts\/4086","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/tenhosaude.com\/en_au\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/tenhosaude.com\/en_au\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/tenhosaude.com\/en_au\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/tenhosaude.com\/en_au\/wp-json\/wp\/v2\/comments?post=4086"}],"version-history":[{"count":3,"href":"https:\/\/tenhosaude.com\/en_au\/wp-json\/wp\/v2\/posts\/4086\/revisions"}],"predecessor-version":[{"id":5770,"href":"https:\/\/tenhosaude.com\/en_au\/wp-json\/wp\/v2\/posts\/4086\/revisions\/5770"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/tenhosaude.com\/en_au\/wp-json\/wp\/v2\/media\/4090"}],"wp:attachment":[{"href":"https:\/\/tenhosaude.com\/en_au\/wp-json\/wp\/v2\/media?parent=4086"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/tenhosaude.com\/en_au\/wp-json\/wp\/v2\/categories?post=4086"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/tenhosaude.com\/en_au\/wp-json\/wp\/v2\/tags?post=4086"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}