{"id":4086,"date":"2023-06-03T22:35:08","date_gmt":"2023-06-04T01:35:08","guid":{"rendered":"https:\/\/tenhosaude.com\/?p=4086"},"modified":"2024-08-20T22:59:43","modified_gmt":"2024-08-21T01:59:43","slug":"neosoro-nafazolina-bula-como-tomar-contraindicacoes-efeitos-colaterais","status":"publish","type":"post","link":"https:\/\/tenhosaude.com\/en\/neoserum-naphazoline-label-how-to-take-contraindications-side-effects\/","title":{"rendered":"Neosoro\u00ae (nafazolin): leaflet, how to take it, contraindications and side effects."},"content":{"rendered":"<h2 id=\"o-que-e\" class=\"wp-block-heading\">What is it?<\/h2>\n\n\n\n<p><strong>Neosoro\u00ae<\/strong> \u00e9 uma marca registrada de um medicamento nasal\u00a0a base de\u00a0<strong>naphazoline hydrochloride<\/strong>, being an antiseptic and nasal fluidizer, widely used to relieve the symptoms of nasal congestion.<\/p>\n\n\n\n<p>It is known for its effectiveness in providing quick and lasting relief, facilitating breathing and promoting a feeling of well-being, making it a reliable product to treat nasal discomfort.<\/p>\n\n\n\n<h2 id=\"para-que-serve\" class=\"wp-block-heading\">What is it for?<\/h2>\n\n\n\n<p>Neosoro\u00ae is indicated for the relief of nasal congestion, which can be caused by different conditions, including colds, flu, rhinitis, sinusitis and allergies.\u00a0<\/p>\n\n\n\n<p>Nasal congestion is characterized by the narrowing of blood vessels in the upper airways, caused by the mucosa, resulting in difficulty breathing, a feeling of heaviness in the nose and general discomfort.\u00a0<\/p>\n\n\n\n<p>Neosoro\u00ae acts directly on these symptoms, providing effective and immediate relief.<\/p>\n\n\n\n<h2 id=\"como-funciona-farmacodinamica-e-farmacocinetica\" class=\"wp-block-heading\">How it works? Pharmacodynamics and Pharmacokinetics<\/h2>\n\n\n\n<p>The active ingredient in Neosoro\u00ae is naphazoline, a substance that is vasoconstrictive. Naphazoline works by stimulating alpha-adrenergic receptors present in the blood vessels of the nose.\u00a0<\/p>\n\n\n\n<p>This action promotes constriction of the vessels, resulting in a reduction in swelling and nasal congestion. In this way, Neosoro\u00ae unblocks the airways, allowing freer and more comfortable breathing.<\/p>\n\n\n\n<p>After nasal application of Neosoro\u00ae, naphazoline is quickly absorbed by the nasal mucosa. It starts to take effect, usually around 10 minutes after application, and its effect lasts between 2 and 6 hours. The substance is metabolized mainly in the liver and excreted mainly through the kidneys.<\/p>\n\n\n\n<h2 id=\"como-devo-usar\" class=\"wp-block-heading\">How should I use it?<\/h2>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Before using, make sure it has not expired.<\/li>\n\n\n\n<li>Place 1 to 2 drops in each nostril (nose), 4 to 6 times a day.<\/li>\n\n\n\n<li>Do not exceed the maximum daily dose of 24 drops.<\/li>\n\n\n\n<li>After use, clean the applicator with a dry tissue and replace the protective cap.<\/li>\n\n\n\n<li>Respect a minimum interval of 3 hours between applications.<\/li>\n\n\n\n<li>Avoid using the product for more than 3 to 5 consecutive days and do not exceed the recommended dose.<\/li>\n<\/ol>\n\n\n\n<p>Remember that Neosoro\u00ae is intended for nasal use only and should not be ingested. To reduce the risk of contamination and transmission of infections, avoid sharing the bottle with other people.<\/p>\n\n\n\n<h2 id=\"contraindicacoes-e-advertencias\" class=\"wp-block-heading\">Contraindications and warnings<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Neosoro\u00ae Adult should not be used by children under 12 years of age. For children over 2 years old, purchase Neosoro\u00ae Infantil.<\/li>\n\n\n\n<li>Pregnant women: use without medical supervision is not recommended.<\/li>\n\n\n\n<li>Do not use if you are allergic to any component of the formula.<\/li>\n\n\n\n<li>It should not be used in people with narrow-angle glaucoma.<\/li>\n\n\n\n<li>During use, it is recommended not to drive vehicles or operate machinery, as the medication may affect ability and attention, causing drowsiness or other effects that may compromise safety in these activities.<\/li>\n\n\n\n<li>People who have the following conditions should inform their doctor before starting and be more careful when using:\n<ul class=\"wp-block-list\">\n<li>bronchial asthma,\u00a0<\/li>\n\n\n\n<li>Cardiovascular problems (heart and blood vessels),<\/li>\n\n\n\n<li>Arterial hypertension (high blood pressure),\u00a0<\/li>\n\n\n\n<li>Hyperthyroidism (excessive thyroid function);<\/li>\n\n\n\n<li>Diabetes mellitus (high glucose levels);<\/li>\n\n\n\n<li>Prostatic hypertrophy (enlarged prostate).\u00a0<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n\n\n\n<h2 id=\"efeitos-colaterais\" class=\"wp-block-heading\">Side effects<\/h2>\n\n\n\n<p>Neosoro\u00ae may cause some adverse reactions. Here we list the main ones:<\/p>\n\n\n\n<p><strong>Temporary local irritation:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Burning<\/li>\n\n\n\n<li>Burning\u00a0<\/li>\n\n\n\n<li>Sneezing<\/li>\n<\/ul>\n\n\n\n<p><strong>General side effects:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Nausea (sickness)<\/li>\n\n\n\n<li>Headache (headache)<\/li>\n\n\n\n<li>Increased blood glucose levels in diabetic patients who use the medication chronically<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Nasal congestion due to rebound effect (condition in which the sudden suspension of treatment leads to the return of symptoms)<\/li>\n\n\n\n<li>Medicinal rhinitis caused by prolonged use of the medication<\/li>\n<\/ul>\n\n\n\n<p><strong>Cardiovascular reactions:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Arterial hypertension (high blood pressure)<\/li>\n\n\n\n<li>Tachycardia (increased heart rate)<\/li>\n\n\n\n<li>Caution in elderly patients with severe cardiac disease and arrhythmias as systemic absorption of naphazoline may aggravate these conditions<\/li>\n<\/ul>\n\n\n\n<p><strong>Endocrine\/metabolic reactions:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Worsening hyperglycemia (excess blood glucose) in patients with diabetes, especially those with diabetic ketoacidosis<\/li>\n<\/ul>\n\n\n\n<p><strong>Neurological reactions:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Somnolence,\u00a0<\/li>\n\n\n\n<li>Easy<\/li>\n\n\n\n<li>Decrease in body temperature<\/li>\n\n\n\n<li>Fatigue<\/li>\n\n\n\n<li>Tiredness<\/li>\n\n\n\n<li>Headache<\/li>\n\n\n\n<li>With the<\/li>\n\n\n\n<li>Insomnia<\/li>\n<\/ul>\n\n\n\n<p><strong>Respiratory reactions:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Epistaxis (nosebleed)<\/li>\n\n\n\n<li>Burning and pain in the nose<\/li>\n\n\n\n<li>Sneezing<\/li>\n\n\n\n<li>Nasal runny and discomfort<\/li>\n\n\n\n<li>Rhinitis<\/li>\n<\/ul>\n\n\n\n<p><strong>Ophthalmic reactions:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Conjunctivitis<\/li>\n\n\n\n<li>Eye irritation and pain<\/li>\n\n\n\n<li>Visual changes<\/li>\n\n\n\n<li>Eye redness and irritation<\/li>\n\n\n\n<li>Pupil dilation<\/li>\n\n\n\n<li>Increased intraocular pressure<\/li>\n<\/ul>\n\n\n\n<p><strong>Other adverse reactions described:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Benzalkonium chloride can cause rhinitis drug when used repeatedly. This manifests as inflammation, swelling and nasal congestion.<\/li>\n\n\n\n<li>Do not ingest the medicine as it is intended for nasal use only. Ingestion can cause side effects such as nausea, vomiting, tachycardia, drowsiness, among others.<\/li>\n<\/ul>\n\n\n\n<p>In case of unusual side effects, it is important to notify the company that manufactures the medicine and also register the incident in the Adverse Drug Event Reporting System \u2013 Vigimed. You can access it through the website:<a href=\"http:\/\/portal.anvisa.gov.br\/vigimed\" target=\"_blank\" rel=\"noopener\"> http:\/\/portal.anvisa.gov.br\/vigimed<\/a>.<\/p>\n\n\n\n<h2 id=\"composicao\" class=\"wp-block-heading\">Composition:\u00a0<\/h2>\n\n\n\n<p>Each mL of Neosoro\u00ae solution may contain:<\/p>\n\n\n\n<figure class=\"wp-block-table is-style-stripes\"><table class=\"has-gray-200-background-color has-background\"><thead><tr><th>Component<\/th><th>Amount<\/th><\/tr><\/thead><tbody><tr><td>Naphazoline hydrochloride<\/td><td>0.5 mg<\/td><\/tr><tr><td>Vehicle qsp (benzalkonium chloride, sodium chloride and water)<\/td><td>Enough quantity to reach 1mL<\/td><\/tr><\/tbody><\/table><figcaption class=\"wp-element-caption\">Composition table of Neosoro\u00ae (naphazoline hydrochloride)<\/figcaption><\/figure>\n\n\n\n<p>*Each mL corresponds to 30 drops.<\/p>\n\n\n\n<p>*Each drop of the solution contains 0.017mg of naphazoline hydrochloride.\u00a0<\/p>\n\n\n\n<p>This information is relevant to ensure the correct dosage and administration of the medication. Consult the leaflet of the specific medication you are using to check the composition and excipients present. There may be variations between different brands\/products.<\/p>\n\n\n\n<h2 id=\"informacoes-tecnicas\" class=\"wp-block-heading\">Technical information:\u00a0<\/h2>\n\n\n\n<p>The information below refers to the active ingredient Naphazoline:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>F\u00f3rmula molecular:\u00a0C<sub>14<\/sub>H<sub>14<\/sub>N<sub>2<\/sub><\/li>\n\n\n\n<li>N\u00famero CAS:\u00a0835-31-4<\/li>\n\n\n\n<li>Massa molar:\u00a0210,274\u00a0g\/mol<\/li>\n\n\n\n<li>Nome IUPAC:\u00a02-(naphthalen-1-ylmethyl)-4,5-dihydro-1H-imidazole<\/li>\n<\/ul>\n\n\n\n<h2 id=\"nomes-comerciais-e-similares-do-neosoro\" class=\"wp-block-heading\">Commercial and similar names of Neosoro\u00ae<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Neosoro\u00ae H2: contains, in addition to naphazoline, benzalkonium chloride, a nasal antiseptic.<\/li>\n\n\n\n<li>Neosoro\u00ae Infantil: a lower concentration of naphazoline (0.25 mg\/mL) and is indicated for children over 2 years old.<\/li>\n\n\n\n<li>Rinosoro: contains only sodium chloride (physiological saline) and does not have a decongestant action, but rather humidifies and fluidifies nasal secretions.<\/li>\n<\/ul>\n\n\n\n<p>There are also other medicines that contain naphazoline in their composition, but with different trade names, such as:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Narix.<\/li>\n\n\n\n<li>Multiserum.<\/li>\n\n\n\n<li>Naridrin.<\/li>\n\n\n\n<li>Nafazol.<\/li>\n\n\n\n<li>Nasolin.<\/li>\n\n\n\n<li>Nasaliv.<\/li>\n\n\n\n<li>Nasoflux.<\/li>\n\n\n\n<li>Nasomax.<\/li>\n\n\n\n<li>Novosoro.<\/li>\n\n\n\n<li>Rinofluimucil: which contains, in addition to naphazoline, acetylcysteine, a mucolytic that helps dissolve nasal mucus.<\/li>\n<\/ul>\n\n\n\n<h2 id=\"interacoes-com-outros-medicamentos\" class=\"wp-block-heading\">Interactions with other medications<\/h2>\n\n\n\n<p>It is important to be careful when using Neosoro\u00ae if you are being treated with medications known as monoamine oxidase inhibitors, such as phenelzine, tranylcypromine and moclobemide. These medications may increase the blood pressure-elevating effects of naphazoline.<\/p>\n\n\n\n<p>Furthermore, if you are taking tricyclic antidepressants such as amitriptyline, imipramine or clomipramine, it is recommended to exercise caution when using Neosoro\u00ae as there may be an increase in blood pressure.<\/p>\n\n\n\n<p>\u00c9 importante lembrar que essas intera\u00e7\u00f5es medicamentosas n\u00e3o s\u00e3o exclusivas da nafazolina, mas \u00e9 essencial considerar essa possibilidade.\u00a0Informe sempre ao seu m\u00e9dico se estiver usando outros medicamentos.<\/p>\n\n\n\n<h2 id=\"superdose-o-que-acontece-se-tomar-acima-do-que-a-recomendada\" class=\"wp-block-heading\">Overdose: what happens if you take more than recommended?<\/h2>\n\n\n\n<p>Excessive application of Neosoro\u00ae can cause adverse effects such as nasal redness, cardiac arrhythmias, decreased or increased heart rate, headache, nausea and vomiting, depression of the Central Nervous System, drop or increase in blood pressure.<\/p>\n\n\n\n<p>If the medication is ingested excessively, seek medical help quickly and take the medication package or leaflet with you. For further guidance, you can also call 0800 722 6001.<\/p>\n\n\n\n<h2 id=\"download-da-bula-original\" class=\"wp-block-heading\">Download the original leaflet<\/h2>\n\n\n\n<p>Click on the button below and download the complete package insert from the Manufacturer Neo Qu\u00edmica.<\/p>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link has-green-background-color has-background wp-element-button\" href=\"https:\/\/tenhosaude.com\/wp-content\/uploads\/2024\/08\/Bula-do-paciente-NEOSORO-cloridrato-de-nafazolina-Neo-quimica-Brainfarma-Tenho-Saude.pdf\">Click here to download the leaflet<\/a><\/div>\n<\/div>\n\n\n\n<p>For more news, visit our website\u00a0<a href=\"https:\/\/tenhosaude.com\/en\/\">I have health<\/a>, follow on Instagram\u00a0<a href=\"https:\/\/www.instagram.com\/tenhosaude\/\" target=\"_blank\" rel=\"noreferrer noopener\">@tenhosaude<\/a>\u00a0and on TikTok\u00a0<a href=\"https:\/\/www.tiktok.com\/@tenhosaude.com\">@tenhosaude.com<\/a>.<\/p>\n\n\n\n<p class=\"has-gray-200-background-color has-background has-small-font-size\"><strong>Sources and bibliography:<\/strong><br><br>This article was manually extracted from the original leaflet of the medicines produced by <a href=\"https:\/\/www.neoquimica.com.br\/nossas-marcas\/Neosoro\" target=\"_blank\" rel=\"noreferrer noopener\">Neo Qu\u00edmica\u00ae 30mL<\/a> in June 2022, under technical supervision of the responsible pharmacist.<br><br>To access the Neosoro\u00ae or Nafazolina leaflet, you can visit the\u00a0<a href=\"https:\/\/consultas.anvisa.gov.br\/#\/bulario\/\" target=\"_blank\" rel=\"noreferrer noopener\">ANVISA electronic leaflet<\/a>\u00a0and search for the manufacturer of your choice.<\/p>","protected":false},"excerpt":{"rendered":"Find out the precise indications for the medicine Neosoro\u00ae and important information about its use, based on its official leaflet. We explain everything in a clear and easy-to-understand way, so that you have complete knowledge about this medicine.","protected":false},"author":1,"featured_media":4090,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[354],"tags":[260,255,257,182,252,254,253,235,258,259],"class_list":{"0":"post-4086","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-saude-mental","8":"tag-alergia","9":"tag-congestao-nasal","10":"tag-gripe","11":"tag-medicamentos","12":"tag-nafazolina","13":"tag-nariz-entupido","14":"tag-neosoro","15":"tag-remedio","16":"tag-resfriado","17":"tag-sinusite","18":"cs-entry","19":"cs-video-wrap"},"jetpack_featured_media_url":"https:\/\/tenhosaude.com\/wp-content\/uploads\/2023\/06\/Neosoro\u00ae-nafazolina-bula-como-tomar-contraindicacoes-e-efeitos-colaterais.-Tenho-Saude.jpg","jetpack_sharing_enabled":true,"jetpack_likes_enabled":false,"_links":{"self":[{"href":"https:\/\/tenhosaude.com\/en\/wp-json\/wp\/v2\/posts\/4086","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/tenhosaude.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/tenhosaude.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/tenhosaude.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/tenhosaude.com\/en\/wp-json\/wp\/v2\/comments?post=4086"}],"version-history":[{"count":3,"href":"https:\/\/tenhosaude.com\/en\/wp-json\/wp\/v2\/posts\/4086\/revisions"}],"predecessor-version":[{"id":5770,"href":"https:\/\/tenhosaude.com\/en\/wp-json\/wp\/v2\/posts\/4086\/revisions\/5770"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/tenhosaude.com\/en\/wp-json\/wp\/v2\/media\/4090"}],"wp:attachment":[{"href":"https:\/\/tenhosaude.com\/en\/wp-json\/wp\/v2\/media?parent=4086"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/tenhosaude.com\/en\/wp-json\/wp\/v2\/categories?post=4086"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/tenhosaude.com\/en\/wp-json\/wp\/v2\/tags?post=4086"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}